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  • Area of employment Veterinary Kit

Kit Description

Specific kit for the qualitative, rapid and specific detection of Babesia spp. in EDTA whole blood samples

Babesiosis or piroplasmosis is a parasitic disease transmitted by ticks.

It can cause severe hemolytic anemia and mortality in all susceptible animal species, including horses, dogs, ruminants, and numerous other domestic and wild species.

It is caused by a protozoan intracellular parasite of red blood cells. Clinical symptoms may vary depending on the resistance and immune status of the host.

Affected individuals experience red blood cell lysis and cyclical release of the parasite (merozoites) which infects other red blood cells until a massive infestation occurs, resulting in hemolytic anemia, hemoglobinuria, high fever, jaundice and, if not treated promptly, death.

Le specie maggiormente colpite sono gli equini (<em<style=”color:#7a7a7a”>Babesia caballi) dove generalmente come sintomo premonitore si osserva una improvvisa caduta delle prestazioni sportive seguito immediatamente dall’anemia e dall’ittero.

Nei cani la babesiosi è generalmente causata da <em<style=”color:#7a7a7a”>Babesia canis, trasmessa dalle zecche, molto diffuse nei nostri paesi, come Rhipicephalus sanguineus.

Generalmente ha decorso grave ma in aree endemiche sono segnalati casi subacuti e cronici.

La babesiosi dei ruminanti è causata da <em<style=”color:#7a7a7a”>Babesia bigemina e <em<style=”color:#7a7a7a”>Babesia bovis, viene trasmessa da zecche del genere Boophilus. Anche nei bovini la sintomatologia clinica è decisamente grave e comprende febbre, emoglobinuria, ittero, anemia fino ad arrivare alla morte.

Il kit è stato testato per i seguenti ceppi del genere Babesia: B. canis, B. rossi, B. gibsoni, B. divergens, B. bovis and B. microti.

* Patent licenses WO 00/28082, WO 01/34790, WO 01/77317, WO 02/24902, WO 01/34838 ** Industrial invention patent no. 0001425753 dated 09.11.2016

The Kit is composed of

Reagents

To perform rapid DNA extraction and specific gene amplification with LAMP technology

BADGE (RFID)

Contains all information relating to the kit, including the lot number and expiration date

TABLET WITHIN ICGENE APP

Con esito in tempo reale della ricerca di Babesia spp nei campioni di sangue analizzati

RAPID BIOMOLECULAR
ANALYSIS

Automatic interpretation of results

The system allows automatic interpretation of the results, real-time visualization and online availability. The sigmoid curves sigmoid curves in correspondence with the positive (+) samples indicate the presence of Babesia spp. The straight indicate that the analyzed samples are negative (or) for Babesia spp.

FEATURES

  • All reagents included and ready to use
  • Rapid RNA and DNA extraction in minutes at controlled temperature
  • LAMP Technology
  • Tablet with App included to allow results to be read directly
  • Customized solutions for laboratories

BENEFITS

  • Portable system also for field analysis
  • Transportation at room temperature
  • Store reagents between +2° and +8° C
  • Results in 60' maximum
  • Reduction of cross-contamination

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